United States securities and exchange commission logo January 6, 2021 Mali Zeevi Chief Financial Officer BioLineRx Ltd. 2 HaMa ayan Street Modi in 7177871, Israel Re: BioLineRx Ltd. Registration Statement on Form F-3 Filed December 31, 2020 File No. 333-251857 Dear Ms. Zeevi: This is to advise you that we have not reviewed and will not review your registration statement. Please refer to Rules 460 and 461 regarding requests for acceleration. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Please contact Laura Crotty at 202-551-7614 with any questions. Sincerely, Division of Corporation Finance Office of Life Sciences cc: Gary Emmanuel